✅ Liver disease (cirrhosis, hepatitis, or bile duct problems) can cause severe itching due to bile buildup in the bloodstream.
✅ Kidney disease leads to toxin accumulation, which triggers chronic itchiness, especially on the back and arms.
📌 Other Symptoms: Fatigue, yellowing skin (jaundice), dark urine, or swelling.
2. Diabetes & High Blood Sugar 🍬
✅ High blood sugar levels can cause dry, irritated skin, leading to persistent itching.
✅ Poor circulation (common in diabetes) leads to itching in the legs and feet.
📌 Other Symptoms: Frequent urination, excessive thirst, tingling hands/feet, slow-healing wounds.
3. Thyroid Disorders (Hypothyroidism or Hyperthyroidism) 🦋
✅ Underactive thyroid (hypothyroidism) causes dry, itchy skin due to reduced oil production.
✅ Overactive thyroid (Graves’ disease) may cause skin irritation and hives.
📌 Other Symptoms: Hair thinning, weight changes, sensitivity to heat/cold, fatigue.
4. Blood Cancer (Lymphoma, Leukemia, or Myeloma) 🔬
✅ Certain blood cancers can cause unexplained full-body itching due to immune system changes.
✅ Hodgkin’s lymphoma is one of the most common cancers associated with severe, persistent itching.
📌 Other Symptoms: Swollen lymph nodes, night sweats, unexplained weight loss.